Approximately 50% of the U.S. population has a gene variant of the MTHFR gene, which provides instructions for your body to convert folate (vitamin B9) to its active form (5-MTHF), which is vital for cellular pathways that drive a whole-body biological process called methylation.*

While converting folate to 5-MTHF isn’t entirely impossible with an MTHFR gene variation, this unique polymorphism can reduce active folate production by up to 70%, which can cause real health concerns down the road.

However, when supplements feature B vitamins that are already in their bioactive forms (and for folate and vitamin B12, that means their methylated forms), folks with an MTHFR gene variant are getting nutrients they can readily use in cells and organs throughout their body (yes, including your brain). 

And remember, 50% of people have these gene variations but most don’t even know it. Since bioavailable B vitamins have no downside for individuals that don’t have a variant, it’s always a good idea to make sure the B’s you’re taking are bioactive and ready to go (just in case).

Here’s a comprehensive list of the exact bioactive B vitamin forms to look for:

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Harmony Evans is an award-winning author of Harlequin Kimani Romance, African-American romance, and so on. Harmony Evans is an award-winning author for Harlequin Kimani Romance, the leading publisher of African-American romance. Her 2nd novel, STEALING KISSES, will be released in November 2013. Harmony is a single mom to a beautiful, too-smart-for-her-own-good daughter, who makes her grateful for life daily. Her hobbies include cooking, baking, knitting, reading, and of course, napping and also review some of the best-selling and popular brands and services in the market and also write comprehensive blogs.


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