The glymphatic system works by bringing cerebrospinal fluid to the brain while we sleep, which removes protein waste products like tau proteins and amyloid beta—which are well known risk factors for Alzheimer’s and dementia.

And for starters, Nedergaard notes, there appears to be a bidirectional relationship between sleep and the glymphatic system, and neurological conditions. Namely, she writes, cardiovascular, neurological, and several inflammatory diseases have all been shown to worsen glymphatic function—as does chronic stress and aging in general.

Further, this toll on the glymphatic system predisposes individuals to neurodegenerative diseases like Alzheimer’s.

But on the flipside, Nedergaard explains, better sleep could mean an improved glymphatic system. “Common approaches that are known to reduce stress and improve sleep and life quality all act by improving glymphatic flow and restoring brain homeostasis,” she adds.


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Harmony Evans is an award-winning author of Harlequin Kimani Romance, African-American romance, and so on. Harmony Evans is an award-winning author for Harlequin Kimani Romance, the leading publisher of African-American romance. Her 2nd novel, STEALING KISSES, will be released in November 2013. Harmony is a single mom to a beautiful, too-smart-for-her-own-good daughter, who makes her grateful for life daily. Her hobbies include cooking, baking, knitting, reading, and of course, napping and also review some of the best-selling and popular brands and services in the market and also write comprehensive blogs.

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